Your heart requires huge amounts of ATP energy to pump blood - it beats 100,000 times a day and 2.92 billion times over an average lifetime.
Each heart cell has thousands of mitochondria - in some cases making up over half the volume of each cell. Why? …because your heart is one of the hardest working organs in your body and needs a constant supply of energy to contract and relax the heart, amongst other functions.
As we get older our mitochondria start to malfunction and deliver less energy to the cells that make up our cardiovascular system. If your mitochondria are not working optimally then it can have a significant effect on the energy available to your heart and your cardiovascular health.
Malfunctioning mitochondria also produce excess free radicals, which cause oxidative damage if not neutralised by antioxidants.
This puts our heart in a state of oxidative stress, which has long been implicated in the development of a number of heart function disorders and is linked to over 200 different diseases. To learn more about heart and oxidative stress, click here >>
Excess free radicals in our vascular system also react with and deplete nitric oxide - a very important molecule that our bodies use to naturally dilate our blood vessels.
The result… as we age our cardiovascular system gradually declines to the point where disease manifests.
People with heart problems also often exhibit CoQ10, L-Carnitine, D-ribose, and/ or magnesium deficiencies.
A third generation of CoQ10 called MitoQ is an important breakthrough. MitoQ is a positively charged form of CoQ10 that is attracted to negatively charged mitochondria. MitoQ is scientifically proven to reach mitochondria in levels between 800 and 1000 times more than traditional CoQ10 supplements and significantly replenishes the mitochondrial free-radical defense system. To learn more about the difference between MitoQ and CoQ10, click here >>
When we deliver high levels of antioxidants to our mitochondria they start operating like they did when we were younger delivering that all important energy to your cells and supporting your cardiovascular health.
MitoQ capsules are now available in a comprehensive, powerful formulation designed to be even more targeted to support heart health and people who have been prescribed statins. MitoQ Heart is designed to support repair of mitochondria and support ATP energy production. MitoQ Heart not only contains scientifically proven MitoQ to repair and reduce oxidative damage, but also L-Carnitine & Magnesium to help increase ATP energy production in your body. MitoQ Heart also contains Vitamin D3. Vitamin D3 has been shown to support heart health via several different mechanisms. It has been shown that normal Vitamin D levels are associated with a healthy cardiovascular system.
Even on it’s own, MitoQ has been shown to support various aspects of cardiovascular health in several studies and more studies are underway to further support this evidence. With the addition of three other ingredients proven to support heart health, MitoQ Heart is a potent formulation.
Steven Sinatra, an experienced and well-known cardiologist, coined the term ‘the awesome foursome’ for heart health, which refers to the four nutrients CoQ10, LCarnitine, Magnesium & D-Ribose.
Mitochondria require each of the “awesome foursome” (CoQ10, L-Carnitine, Magnesium & D-ribose) to generate ATP. While CoQ10 and L-Carnitine are fundamental to the ATP recycling process, D-ribose is necessary for de novo ATP synthesis. Metaphorically, D-ribose helps fill the body’s gas tank while LCarnitine and CoQ10 help the body convert fuel to energy. Literally, D-ribose is a structural component of the ATP molecule, and L-Carnitine and CoQ10 help recycle ATP by transporting fatty acids across mitochondrial membranes and shuttling electrons back and forth between enzymes, respectively. Co-Q10 then acts as an antioxidant to protect mitochondrial membranes from free-radical damage. Like a spark plug central to both processes, magnesium “turns on” the enzymes that drive the entire metabolic reaction.
Depending on the individual, supplementation with any or all of the “awesome foursome” may be the key to maintaining energy and overall health. At around age forty, endogenous production of CoQ10 and L-Carnitine generally starts to decrease, explaining why people commonly associate lack of energy with “middle age.”
Vitamin D3 has also been shown to support heart health via several different mechanisms.
“It’s my No.1 supplement with definitive proven results.”
To learn more about Mary’s experience with MitoQ, click here >>
Cardiovascular health is a general term used to encompass the health of the heart and blood vessel system. Cardiovascular disease is the leading cause of death in developed countries. Nearly 2 million people in Europe die from cardiovascular disease every year and in the United States more than a third of the population live with a cardiovascular condition at any one time.
It accounts for 30% of deaths annually in NZ. Every 90 minutes, a New Zealander dies from heart disease, with one in twenty adults diagnosed with heart disease (>165,000).
A key reason is that as we get older our mitochondria start to malfunction and deliver less energy to the cells that make up our cardiovascular system. Mitochondria are the tiny organelles that provide power to your cells. Present in almost every cell in our body, mitochondria take the food we eat and the air we breathe and make ATP, the energy molecule that powers our cells.
Unfortunately, when mitochondria are malfunctioning they also start producing excess reactive oxygen species (free radicals), stressing the cell further and causing damage if they are not neutralised by antioxidants. This puts our heart in a state of oxidative stress, which has long been implicated in the development of a number of disorders of heart function and is linked to over 200 different disease states. For more information regarding oxidative stress, click here >>
To add insult to injury, excess free radicals in our vascular system react with and deplete nitric oxide - a very important molecule that our bodies use to naturally dilate our blood vessels. The result … as we age our cardiovascular system gradually declines to the point where disease manifests.
Everyone needs a sustained and healthy pool of ATP to fuel bodily functions, and the heart needs more than most parts of the body. Cells require large amounts of ATP to contract and relax the heart, amongst other functions. The body’s preferred method of energy production is to recycle ATP. Eighty to ninety percent of ATP is recycled in the mitochondria, then released into the fluid portion of cells to be used for energy, so if the mitochondria are suffering from oxidative damage, they may not be producing sufficient energy for the heart to function optimally.
It is a little known fact that you have thousands of mitochondria in every one of your heart cells - in some cases making up over half the volume of each cell. Why? ...because your heart is one of the hardest working organs in your body and needs a constant supply of energy.
Your heart consumes huge amounts of ATP as it pumps blood around your body 24/7, beating 100,000 times a day and 2.92 billion times over an average lifetime.
To get all the energy/ATP your heart requires mitochondria by the thousands in each of your heart cells. If your mitochondria are not working optimally then it can have a significant effect on the energy available to your heart, which can have a significant impact on your cardiovascular health.
Protecting your mitochondria and reducing oxidative stress with antioxidants should be something that anyone over 40 and anyone concerned about their cardiovascular health should aim for.
However, conventional antioxidants have turned out to be largely ineffective. This is thought to relate to their inability to penetrate the mitochondria to quench the free radicals at the source.
Your mitochondria’s natural antioxidant is CoQ10. Supplemental CoQ10 is recommended to patients by many doctors all around the world for cardiovascular health. However, what the suppliers of CoQ10 don't tell you is that it is unable to reach the mitochondria in levels that have a meaningful effect.
A healthy ATP energy pool may be your fountain of youth. While you can’t take ATP as a pill or vitamin, you can give your body the next best thing: substances with which it can make ATP. Supplementing with MitoQ Heart can support repair of mitochondria and boost ATP production, thus providing potent support for heart health. By directing nutrition to the mitochondrial level, you can improve your quality of life and possibly increase your longevity, especially if you’re taking pharmaceutical medications such as statins (which further deplete CoQ10 levels*) and/or living with a cardiovascular condition.
People with heart problems often exhibit CoQ10, L-Carnitine, D-ribose, and/or magnesium deficiencies. As the heart is one of the most responsive organs in the body for targeted nutritional supplementation, supplementation is a must. By enhancing ATP synthesis and recycling, and promoting more efficient metabolism in mitochondria, MitoQ Heart supports healthy heart function. Patients should always consult with their physicians before adding nutritional supplements to a pharmacologic program.
People on statins to reduce cholesterol are even more likely to benefit as statins deplete the body’s natural CoQ10 levels. In a double-blind, placebo-controlled study(1), it has been shown that statins can reduce serum levels of Coenzyme Q10 by as much as 40%.
People taking statins to lower their cholesterol levels can experience side effects such as muscle pain, nausea and diarrhoea, liver and kidney damage, and even increased blood sugar or type 2 diabetes. Some people experience more serious problems, including something known as rhabdomyolysis. This process occurs when muscle cells break down. As muscles collapse, a muscle protein is released into the bloodstream. This in turn can cause severe kidney problems.
The UMMC also indicates that CoQ10 may function as a natural treatment to help support healthy cholesterol. While there aren’t enough studies to confirm how well it works, it may be possible to combine CoQ10 with statins for better results without the side effects.
To learn more about the use of MitoQ to support heart health, visit MitoQ Ongoing Research >>
 Ghirlanda G, Oradei A, Manto A, Lippa S, Uccioli L, Caputo S, Greco A, Littarru G (1993). "Evidence of plasma CoQ10-lowering effect by HMG-CoA reductase inhibitors: a double-blind, placebo-controlled study". J Clin Pharmacol 33 (3): 226-9. PMID 8463436.
Powerful support for optimal heart health.
For beautiful, healthy skin.