But beyond its role in the energy production process, there are several other beneficial effects of L-carnitine from supporting heart and brain function to maintaining exercise performance and recovery.
What is carnitine?
Derived from an amino acid, carnitine is the generic term for several compounds, including L-carnitine, acetyl L-carnitine, propionyl-L-carnitine, L-carnitine L-tartrate and D-carnitine. L-carnitine is the most common form of carnitine found in the body.
Carnitine is naturally produced by the brain, liver and kidneys from the amino acids methionine and lysine. It's also present in many foods, particularly animal-derived foods like dairy products and meat, as well as dietary supplements.
L-carnitine and energy production
L-carnitine plays a crucial role in mitochondrial function and energy production by facilitating the transport of long-chain fatty acids into the mitochondria, which are the powerhouses of cells. The mitochondria are responsible for generating the majority of a cell's energy in the form of adenosine triphosphate (ATP).
Fatty acids are a major fuel source for the production of ATP, particularly during prolonged or high-intensity exercise, or when glucose availability is limited. However, fatty acids cannot directly cross the mitochondrial membrane to be metabolized for energy. This is where carnitine comes into play.
Carnitine acts as a carrier molecule, forming a complex with fatty acids, known as acylcarnitine and shuttling them across the mitochondrial membrane. Once inside the mitochondria, fatty acid oxidation occurs, where the complex is broken down and eventually leads to the production of ATP through oxidative phosphorylation.
In addition to its role in fatty acid transport, carnitine also helps remove toxic byproducts generated during fatty acid metabolism. By removing these toxic compounds, carnitine helps support the proper functioning of mitochondria and supports overall energy production.