The overlooked link between blood glucose and heart health

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Why heart health is a concern when glucose control is compromised

Uncontrolled blood glucose, which can wreak havoc on many systems of the body, including the brain, eyes, and especially the heart. In fact, the heart is one of the first systems showing dysfunction when systems that control blood glucose become unbalanced. As the heart becomes more and more strained from poor glucose metabolism and low energy output, it loses its ability to adequately pump blood throughout the body. Poor blood flow leads to many other challenges such as inability to perform everyday tasks, such as walking upstairs, and great limits an individual’s quality of life and longevity.

A new approach to supporting cardiometabolic health

A recent study presented at the British Cardiovascular Society conference indicated that Mitoquinone, also known as MitoQ® or Mitoquinol Mesylate, may help people with blood glucose concerns keep their heart healthy.

Promising results from the MitoQ* study

Henry Proctor, the lead author and Eylem Levelt, the senior author, explained that Mitoquinone supplements given for 4 months improved heart efficiency in pumping and using energy. In fact, the 70 patients who took Mitoquinone supplements had their heart’s energy use improve up to 15%. This is due to Mitoquinone’s unique ability to reduce mitochondrial oxidative stress, which can interfere with how well heart cells can make energy.

How MitoQ® supports cardiovascular function

Mitoquinone, popularly known as MitoQ® Mitoquinol, commercially available as a dietary supplement, has been shown to improve mitochondria function in subjects with heart function concerns. Moreover, MitoQ® helps improve vascular function and blood flow in healthy older adults. MitoQ®’s capability as a potent mitochondria antioxidant that combats age-related damage in animal models, suggests it can help many aspects of cardiovascular health.

In this recent study, participants’ hearts functioned better under physical stress, recovered more efficiently after exercise, and showed signs of improved blood vessel flexibility, an important indicator of good heart health. These results suggest that MitoQ may help the heart stay more flexible and resilient.

Safety and what comes next

Importantly, none of the subjects reported any adverse events or bad side effects, meaning Mitoquinone (MitoQ®) may be easy to incorporate into a lifestyle plan.

While further research is underway, these findings offer hope to the millions of Americans concerned about their heart health and blood glucose, showing that early intervention with a targeted antioxidant like MitoQ* could help support long-term cardiovascular health.

*MitoQ® is self-affirmed GRAS up to 20mg per day as a commercially available dietary supplement

REFERENCES

  • 1.

    Cousins, J. (2025, June 3). Supplement could prevent heart disease in Type 2 diabetes patients. Nutraceutical Business Review.

  • 2.

    Blackwood, H. (2025, June). Reversing early diabetes‑related heart failure through MitoQ. PubMed.ai/Medium.

  • 3.

    Rossman, M. J., Santos‑Parker, J. R., Steward, C. A., Bispham, N. Z., Cuevas, L. M., Rosenberg, H. L., & Seals, D. R. (2018). Chronic supplementation with a mitochondrial antioxidant (MitoQ) improves vascular function in healthy older adults. Hypertension, 71(6), 1056–1063. https://doi.org/10.1161/HYPERT...

  • 4.

    Murphy, M. P., & Smith, R. A. J. (2007). Targeting antioxidants to mitochondria by conjugation to lipophilic cations. Annual Review of Pharmacology and Toxicology, 47, 629–656. https://doi.org/10.1146/annurev.pharmtox.47.120505.105110

  • 5.

    Jia, G., Hill, M. A., & Sowers, J. R. (2018). Diabetic cardiomyopathy: an update of mechanisms contributing to this clinical entity. Circulation Research, 122(4), 624–638. https://doi.org/10.1161/CIRCRESAHA.117.311586

  • 6.

    Donato, A. J., Machin, D. R., Lesniewski, L. A., et al. (2023). Attenuated vascular endothelial dysfunction in late-onset postmenopausal women is mediated by reduced mitochondrial oxidative stress: Contribution of the serum lipidome. American Journal of Physiology - Heart and Circulatory Physiology, 325(2), H305–H318. https://doi.org/10.1152/ajpheart.00094.2023

  • 7.

    Tracy, A. M., et al. (2023). A mitochondrial-targeted ubiquinol (MitoQ) improves immune cell bioenergetics in patients with heart failure with preserved ejection fraction. American Journal of Physiology - Cell Physiology, 325(4), C723–C735. https://doi.org/10.1152/ajpcell.00123.2023

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MitoQ Pure

Contains a full dose of MitoQ Mitoquinol (also known as Mitoquinone), our world-first mitochondria-targeted antioxidant:

- Targets mitochondria to combat cellular aging.
- Enhances energy and & metabolic health.
- Reduces oxidative stress for healthier aging.
- Supports overall vitality and & longevity.

MitoQ pure bottle

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