Cellular reactions produce waste products called free radicals. Free radicals can cause damage to our cells if they are not neutralized by antioxidants. Oxidative stress is the state our body is put in when the levels of antioxidants in our body are not high enough to counteract the damaging effect of free radicals. Mitochondrial dysfunction is now understood to be present in hundreds of different health conditions. Taking an antioxidant supplement such as MitoQ® boosts our own supply of antioxidants which can reduce free radical damage and therefore oxidative stress.
Free radicals are a by-product of almost every biochemical reaction. Normally, our body keeps these electron-stealing atoms under control with endogenously produced antioxidants such as Coenzyme Q10 (CoQ10); however, aging, illness, mitochondrial damage, and exposure to environmental toxins all serve to reduce our own supply of antioxidants and increase free radical production. Free radicals that are left unchecked can inflict severe damage on whatever cellular component they come into contact with, be it fat cells, protein, DNA or RNA. This can damage to the cell and ultimately lead to cell death and puts our body in a state known as oxidative stress.
In addition, research has shown that oxidative stress is thought to be a major contributor to the aging process, both at the cellular level as well as contributing to the external visible signs of aging.
Lipids are particularly susceptible to damage from free radicals, and oxidative stress that involves lipids is called lipid peroxidation. As well as being a major source of energy storage, lipids are also crucial in the production of hormones, vitamins and cell membranes. When lipid peroxidation occurs, free radicals steal electrons off lipids within the cell membrane which increases the permeability of the membrane allowing foreign substances to enter the cell and the contents of the cell to leak out. This changes the make-up of the cell and can disrupt a number of vital biochemical processes within the cell eventually leading to cell death. Peroxidation is believed to be involved in cellular aging and in various health conditions.
Amino acids are the building blocks of proteins. Protein oxidation during oxidative stress breaks vital bonds that hold amino acids together and disrupts many biochemical processes and the formation of DNA and RNA. Protein oxidation has been linked to numerous serious cardiovascular, neurological and metabolic health conditions.
We can limit the amount of oxidative stress placed on our body by eating and living healthily and doing at least 30 minutes of physical activity every day. We can also take antioxidants to supplement our diet, such as CoQ10. MitoQ® is a revolutionary formulation of CoQ10 that is taken up directly by the mitochondria of the cell, replenishing antioxidant reserves right at the site of many biochemical reactions, helping to reduce oxidative stress.
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