MitoQ and your immune system

“For immunologists, mitochondria can be the powerhouse of immunity along with their role as the powerhouse of the cell.” – Frontiers in Immunology, July 2018 

Mitochondria and immunity: How MitoQ powers your immune system 

We often hear that mitochondria are the 'powerhouses of the cell'—but did you know they’re also the powerhouses of immunity? As highlighted in Frontiers in Immunology (July 2018), immunologists now recognize mitochondria as central players in immune defense. 

What is the immune system? 

This is the part of your body that is your defense mechanism. The immune system is made up of many body parts including the bone marrow, thymus and lymph nodes. They communicate and work together to keep us healthy and functioning at our best.

Your skin acts as a protective barrier between your body and the external environment, while internally, specialized cells such as macrophages, T-cells, and natural killer cells help regulate interactions and maintain balance within the body.

Mitochondria: The powerhouses of immunity 

Several studies have shown that immunity and mitochondria are interlinked. Recent findings have shown that mitochondria regulate immune responses, while leukocytes (a white blood cell) need a reliable mitochondrial network. Therefore, keeping your mitochondria healthy is very important. 

Mitochondria regulate immune cell signaling, activation, and survival. They produce CoQ10, a key antioxidant, and generate reactive oxygen species (ROS)—both necessary for immune responses. But as we age, CoQ10 production declines, tipping the balance toward oxidative stress and weakening our immune defenses. 

Why supporting your immunity matters 

Think of your immune system as your body’s personal security team - it’s constantly scanning for unexpected changes, neutralizing potential incoming threats, and keeping everything running smoothly behind the scenes. But just like any team, it performs best when it’s well-supported. When your immune system is strong, you’re more resilient to year-round changes, less likely to feel run down, and better equipped to bounce back from stress. On the flip side, an unequipped immune system can leave you vulnerable to stress, fatigue, and poor overall health. That’s why giving your immunity a helping hand, through good nutrition, sleep, exercise, and mitochondrial support like Mitoquinol, isn’t just smart, it’s proactive. 

How MitoQ’s unique ingredient Mitoquinol fuels a thriving immune system 

Mitoquinol isn’t just a fancy form of CoQ10. It’s a molecule designed to go where regular antioxidants can’t: deep into your mitochondria. This matters because your immune cells, like T-cells and macrophages, are incredibly energy-hungry and rely on healthy mitochondria to function at their best. Mitoquinol helps neutralize free radicals right at the source, reducing oxidative stress and protecting your cells from damage. In clinical studies, Mitoquinol has been shown to boost natural antioxidant defenses like glutathione peroxidase (GPx), which is crucial for breaking down harmful peroxides in immune cells. It also supports vascular health, which is essential for immune cell circulation. And because Mitoquinol is absorbed into mitochondria more efficiently than generic CoQ10, it delivers targeted support where it's needed most to help keep your immune system thriving. Whether you're looking to stay resilient during seasonal shifts or bounce back from stress, Mitoquinol helps your immune system stay energized, balanced, and ready to respond. 

What the latest science says about MitoQ and immunity 

Recent studies continue to reinforce the role of mitochondria - and MitoQ’s patented ingredient Mitoquinol specifically - in immune system regulation. A 2025 study published in Nature revealed that mitochondrial DNA (mtDNA) damage and its release into the cytosol can trigger chronic inflammation, a process known as inflammaging. This underscores the importance of maintaining mitochondrial integrity to prevent age-related immune changes. Mitoquinol, a mitochondria-targeted antioxidant, has shown promise in reducing oxidative stress and preserving mitochondrial function. In a clinical trial, Mitoquinol has been shown to reduce mtDNA damage by up to 25%.

Everyday immune system support 

To stack the odds in your favor and keep your immune system in top shape: 

1. Wash your hands often 

Your skin is your first line of defense, and clean hands help prevent the spread of bacteria. Regular handwashing reduces your exposure to external factors that can compromise your immune system. 

2. Eat plenty of fruits and veggies 

A colorful diet rich in vitamins, minerals, and antioxidants fuels your immune cells. Nutrients like vitamin C, zinc, and beta-carotene found in produce help your body reduce inflammation. 

3. Exercise regularly 

Moderate physical activity boosts circulation, helping immune cells move freely and do their job more efficiently. It also reduces stress hormones that can suppress immune function. 

4. Avoid smoking 

Smoking damages lung tissue and impairs the function of immune cells in the respiratory tract. It also increases inflammation and oxidative stress, making it harder for your body to fight off threats.

5. Get quality sleep 

Sleep is when your body repairs and regenerates—including your immune system. Poor sleep can reduce the production of protective cytokines and antibodies, leaving you more vulnerable. 

Final Thoughts 

Your immune system is a complex, dynamic network that works tirelessly to keep you healthy- and your mitochondria are right at the heart of it. From powering immune cells to regulating normal inflammatory responses and oxidative stress, mitochondria play a starring role in your body’s defense strategy. That’s why supporting mitochondrial health with targeted antioxidants like Mitoquinol, the primary ingredient in MitoQ Pure, isn’t just about boosting energy - it’s about building resilience from within. Whether you’re navigating seasons, managing stress, or simply aiming to feel your best, nurturing your immunity through smart lifestyle choices and mitochondrial support is one of the most impactful things you can do. Here’s to staying strong, energized, and ready for whatever life throws your way.