In the beginning
Thousands of years ago, humans didn't eat sugar; our primary source of food was berries, fruit, vegetables, nuts and, occasionally, meat brought home from a hunt. Our bodies are optimized for low-carb diets and plenty of exercise to burn the natural carbohydrates humans traditionally consumed.
Our bodies aren't coping
These days, we consume a lot more sugar as it can be hidden in the pre-prepared and fast food options we tend to go for due to their convenience. Not to mention the processed sugar we eat in snacks and treats.
Additionally, our modern lifestyles are often relatively sedentary. Less exercise also means we produce fewer mitochondria (the energy sources of our cells), so our capacity to burn sugar is reduced.
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Sugar is the enemy
Not only is sugar considered detrimental to our waistline and to our teeth, it's also the enemy of our mitochondria and contributes to many metabolic health issues. Consuming excess sugar puts the mitochondria under stress, causing them to emit free radicals. This is called oxidative damage.