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MitoQ Healthy Living Blog

Tackling Alzheimer’s disease from a different angle


Despite their prevalence, we lack effective treatments for neurodegenerative disorders such as Alzheimer’s disease. Research suggests treatments that target alterations in cellular components and oxidative stress, such as antioxidants may have a bigger role to play.

Alzheimer’s old lady

Alzheimer’s disease (AD) is an irreversible, progressive brain disorder that slowly destroys memory and thinking skills, eventually robbing people of their ability to carry out the simplest tasks or remember loved ones.


There are certain diagnostic features about AD that make it different from other forms of dementia. The most defining feature is the deposition of a specific type of protein called amyloid β into fragments or plaques in areas of the brain serving memory and cognition. Other features include neurofibrillary tangles (twisted protein threads inside nerve cells), mitochondrial dysfunction, nerve inflammation and oxidative stress.


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This review, published in Frontiers of Pharmacology, discusses various investigational and established antioxidants and other compounds that have been tried in AD and other neurodegenerative disorders such as Parkinson’s disease, Huntington’s disease, and Amyotrophic Lateral Sclerosis. The discussion includes targeted antioxidants such coenzyme Q10, creatine, curcumin, and omega-3 polyunsaturated fatty acids.

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