Lipids. A Big Source Of Oxidative Stress In Cancer Patients

Over one hundred different diseases are termed “cancer”. Although the exact cause of most remains unknown, high levels of free radicals and increased levels of oxidative stress are common findings among sufferers.

Scientists already know that oxidative stress irreversibly damages various cell components including lipids (fats), proteins, carbohydrates and DNA. 

As cancer progresses, tumors have an increased need for glucose which leads to insulin resistance and blood sugar challenges. Protein metabolism also increases as the body searches for an alternative energy source, resulting in massive losses of muscle tissue.

Conversely, lipid levels are typically increased, as the authors of this study Oxidative Stress and Plasma Lipoproteins in Cancer Patients demonstrate.  Nearly 30% of cancer patients exhibited high cholesterol levels and over 58% had low levels of HDL (typically referred to as “good” cholesterol). This unfavourable lipid profile is thought to contribute to a higher lipid breakdown rate, generating significant oxidative stress.

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Topics: All Blog Articles, Mitochondrial Health

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