Men’s health is a concept utilized to describe the physical, mental, and social well-being of men. An unfortunate aspect of men’s health is that it is often misconstrued as a macho form of health, and because of this, many companies will pander to the idea of machoness and masculinity and try to sell un-proven or poorly researched supplements on the basis of improving masculine features and traits.
In reality, men’s health is simply how health topics pertain to men. Disbanding the myth behind men’s health can allow the entire category to support a wider audience of men and ensure that they get the most accurate and best available science and research-backed information.
It is no secret that men and women differ, and having a dedicated understanding of what benefits you could see from a supplement, treatment, or therapy based on your gender can help to ensure you are getting the very best option for you and your specific needs.
Below is a closer look at the health benefits that CoQ10 may be able to provide to men. While this article focuses mainly on men, many of the benefits described could pose similar benefits in women.
Differences in men and women
While one would think that oxidative damage impacts people regardless of sex, there are emerging studies that illustrate a potential sex-specific difference in antioxidant volume in men versus women.
A 2016 study in Germany looking into differences in serum CoQ10 of 860 individuals found that men, regardless of age, had a higher level of cholesterol-adjusted CoQ10 levels than women. While the study did not look into the underlying reason for the discrepancy, it does pose the question as to whether or not women are more susceptible to oxidative stress or if men need a higher antioxidant capacity to stay protected against ROS.
Another study in 2017 aimed to look at the specific differences in levels of oxidative stress in men and women and concluded that in fact, the latter is true in that men seem to have higher levels of ROS than women. This finding aligns with the fact that men have a higher chance of developing some oxidative stress-related ailments and diseases such as cardiovascular-related diseases.
A factor that appears to be similar across genders from the study was a decline in CoQ10 in its redox form which is the form that protects against oxidative stress. This finding has been found in many studies and suggests a potential benefit to supplementing CoQ10, especially as age increases.
Cellular health support
Cellular health is a concept of looking at health from a micro-perspective rather than a macro. With cellular health, the emphasis is on supporting your cells to allow them to work to the best of their abilities.
CoQ10 is a molecule that is integral to proper cellular health within cells. It plays an important role in the way cells derive energy, how membranes protect themselves, and how the cell mitigates reactive oxygen species.
Electron transport chain
Nearly every cell within your body, excluding red blood cells, contains a small compartment known as the mitochondria. The mitochondria are the powerhouse of the cell and it converts readily available carbohydrates and oxygen and creates the energetically useful molecule ATP. ATP helps to run a ton of different cellular machinery and ensure all necessary chemical reactions have the energy needed to work.
The way ATP is derived from the mitochondria is complex and it involves a lot of biochemistry, movement of electrons, and an enzyme known as ATP synthase that spits out ATP at the end of the process. One important step in this process is known as the electron transport chain and this is where CoQ10 plays a role.
Within the electron transport chain, CoQ10 acts as an electron shuttle transporting electrons and assisting with membrane proteins known as complex I and complex II. The ultimate role is that CoQ10 assists the production of ATP within the cell. If CoQ10 levels seem reduced it can reduce the cell’s ability to work as efficiently as possible and result in a slower ATP yield.
Another role that CoQ10 plays is in protecting the membranes of the cell, especially that of the mitochondria. During the production of ATP, a high concentration of reactive oxygen species (ROS) is created and contained within the mitochondria. Reactive oxygen species have the potential to cause damage to cellular componentry because they are highly unstable molecules that will steal electrons from nearby molecules, membranes, and structures.
CoQ10 is found within the membranes of components like the mitochondria and other organelles that are frequently exposed to reactive oxygen species. CoQ10 acts as an antioxidant in this manner and essentially keeps reactive oxygen species at bay to avoid oxidative stress placed on the cell.
CoQ10 is one of the very few lipophilic antioxidants within the body, and as such, it is of importance for generalized protection against radical oxygen species and a preventative to oxidative stress. CoQ10 specifically helps to mitigate cell membrane damage in the form of lipid peroxidation.
As a general antioxidant within the body, CoQ10 can be found within lipoproteins in the blood and can be found in higher concentrations in high energy-consuming organs such as the heart, kidneys, liver, and lungs. Higher energy usage can subsequently expose organs to more reactive oxygen species and the higher concentration of CoQ10 helps to keep the balance in place.
Benefits on general health
While it is nice to know that CoQ10 can protect your body, it is most likely more practical for most people to have a broader understanding of how CoQ10 can support their everyday life and overall wellbeing.
Male fertility is an important aspect for men looking to one day start a family, and male infertility poses a potential roadblock to that reality. Male infertility can be caused by many variables including low sperm production, physical blockages, defective sperm, or even slow-moving sperm. New studies are even revealing that there may be a connection between infertility and mitochondria.
A study from the University of the Republic, Montevideo, found that sperm motility and speed seemed to be related to the respiratory status of the mitochondria within the sperm. Low mitochondrial respiratory efficiency is associated with low CoQ10 levels and this link shows potential for CoQ10 to help support male fertility.
The mitochondria are the basis for your energy at a cellular level and having supported mitochondria could help to support more natural and sustained energy levels.
A great way to think about it is in terms of an electrical grid. In the U.S. there are thousands of powerplants that are all interconnected and provide the country with its power supply. The mitochondria can be thought of like all of those power plants and the body can be thought of as the country as a whole. Supporting each individual powerplant through supplementation of CoQ10 can ensure they are working as efficiently as possible to give you the very best energy level your body can provide.
The brain is one of the most power-hungry organs in the human body. The brain makes up a small amount of your overall mass, but it consumes up to 20% of your daily energy intake. The brain has many duties including directing involuntary vital functions, regulating homeostasis, and even your ability to think.
The brain is composed of billions of cells known as neurons, and each of these cells needs the support of the mitochondria to function at its best. Mitochondrial decline can lead to brain fog and other noticeable changes. Supplementing CoQ10 can be helpful, but oftentimes CoQ10 supplements are poorly absorbed into the mitochondria and can have a hard time passing through the blood-brain barrier and implementing into the neuronal mitochondria.
MitoQ is a modified version of CoQ10 that is much more easily available to the mitochondria and able to readily cross the blood-brain barrier where it can help support more mental clarity and your brain at a cellular level.
In summary, CoQ10 is a potent lipophilic antioxidant in addition to an important molecule in the proper functioning of the mitochondria. CoQ10 is found throughout the body and recent studies have shown that men may be at greater risk for oxidative stress-related issues.
Taking a CoQ10 supplement like MitoQ can help to support a healthier oxidative balance within the body and help men to support their health and wellbeing at a cellular level.
Explore the different MitoQ formulas here and get the support exactly where you need it, men and women alike.