3 ingredients for stress and burnout

While you can’t supplement your way to a stress-free life , adding in some beneficial nutrients on top of a healthy diet and lifestyle can do wonders for the way your body copes with everyday stressors.

Ashwagandha

As one of the herbs traditionally used in the ancient Indian practice of Ayurvedic medicine, Ashwagandha is an adaptogen (anti-stress agent) otherwise known as the botanical name Withania somnifera. In traditional Ayurveda, Ashwagandha has been used for thousands of years to promote focus, memory, happiness, vitality, and longevity among many other purposes. The smell of the root is comparable to the scent of horses (“ashwa”), hence the name Ashwagandha refers to the herb’s scent and its ability to “give the power of a horse”.

In clinical settings, Ashwagandha has been shown to have benefits of:

• Decreased feelings of stress by up to 44%.
• Improved quality of sleep by 72%.
• Decreased serum cortisol by up to 30.5%.
• Improved happiness / mood scores by up to 24.49%.

MitoQ adrenal +balance contains 250mg of Sensoril® Ashwagandha (root) extract

Sensoril® Ashwagandha has an optimized extraction process, with a standardized composition of bioactives, consistent quality control, and effective results backed up by numerous safety studies and human clinical trials. Glycowithanolides are key constituents within the Sensoril® ingredient. These glycowithanolides are thought to mimic natural stress-reducing hormones within the body, decreasing markers of stress – like the hormone cortisol – in the blood and promoting relaxation. Therefore, it is proposed that Sensoril® Ashwagandha can reduce both the feeling of stress as well as the biochemical signs of stress.*

*Sensoril® is a registered trademark of Natreon, Inc.

Magnesium

Magnesium is a crucial mineral involved in over 600 reactions in the body. It has far-reaching effects that benefit energy production, brain health, cardiovascular function, sleep, athletic performance and so much more. Studies suggest that the typical US adult gets less than 50% of the daily recommended intake of magnesium, and as the fourth most abundant mineral in the body. As a cofactor in so many biochemical reactions within the body, magnesium is key for many processes involved in energy, performance and the stress response.

Magnesium regulates neurotransmitters, which can lead to improved mood and mental health by helping to relieve feelings of anxiety and stress. This crucial mineral has also been linked to improved sleep quality.

Different forms of magnesium:

• Magnesium citrate helps with digestion regulation by acting as a laxative in certain amounts. It also helps to maintain bone health and support muscle and nerve function while supporting normal heart rhythm.
• Magnesium threonate is able to easily cross the blood-brain barrier, making it an excellent choice for boosting cognitive health and helping the brain to function optimally.
• Magnesium glycinate is readily absorbed by the body, so it offers a range of different health benefits. From relieving muscle cramps from exercise and the common symptoms of premenstrual syndrome to managing blood sugar levels and soothing anxiety, this form of magnesium plays an important role in many bodily functions.

MitoQ® Mitoquinol Mesylate

Your body is made up of over 37 trillion cells that help you live, breathe and function. Inside almost every one of your cells are tiny organelles called mitochondria, which produce their own energy. As a by-product of producing energy for you to function, mitochondria create free radicals – which are the main cause of oxidative stress in the body.

Once this happens, your cells spend less time and energy doing all those important jobs your body requires, and more time engaging a cell stress response to fight free radical damage. While mitochondria can self-manage free radical build-up by producing antioxidants, your body's antioxidant levels begin to naturally decline as you age – leaving free radicals exposed within your body. Additionally, our day-to-day lives expose us to even more free radicals through stressors such as pollution, UV radiation, poor diet, lack of (or too much!) exercise, too little sleep, smoking, life stress and drinking alcohol – making the battle to balance them that much harder.

Patented MitoQ® Mitoquinol Mesylate is a targeted antioxidant found in all MitoQ brand dietary supplement products that addresses cell stress at the body’s source – because when your cells are functioning optimally, you’re better able to cope with everyday stressors.

Clinical trials and claims related to MitoQ®’s antioxidant ability as a single ingredient:

• MitoQ reduces oxidative stress in the cell *(1)
• MitoQ supports our natural antioxidant capacity* (2,3,4)
• Lessens the impact of free radicals* (5,4)
• Reduced reactive oxygen species (ROS) by up to 48%* (4)

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

References:

1. Williamson, J., Hughes, C. M., Cobley, J. N., & Davison, G. W. (2020). The mitochondria-targeted antioxidant MitoQ, attenuates exercise-induced mitochondrial DNA damage. Redox biology, 36, 101673. https://doi.org/10.1016/j.redo...;

1. Pham, T., MacRae, C.L., Broome, S.C. et al. MitoQ and CoQ10 supplementation mildly suppresses skeletal muscle mitochondrial hydrogen peroxide levels without impacting mitochondrial function in middle-aged men. Eur J Appl Physiol 120, 1657–1669 (2020). https://doi.org/10.1007/s00421...;

1. Jurkuvenaite, A., Benavides, G. A., Komarova, S., Doran, S. F., Johnson, M., Aggarwal, S., Zhang, J., Darley-Usmar, V. M., & Matalon, S. (2015). Upregulation of autophagy decreases chlorine-induced mitochondrial injury and lung inflammation. Free radical biology & medicine, 85, 83–94. https://doi.org/10.1016/j.freeradbiomed.2015.03.039

1. Aminizadeh, S., Lee, J., Zarezadehmehrizi, A., Najafipour, H., Ahmadi, M. A.-D., Moflehi, D., Rashidzadeh, H., & Park, Y.. (2023). MitoQ Supplementation During Vigorous Training Improves Reactive Oxygen Species, Glutathione Peroxidase, and miRNAs Regulating Vascular Inflammation in Cyclists. Brazilian Archives of Biology and Technology, 66, e23220914. https://doi.org/10.1590/1678-4324-2023220914

1. Rossman MJ, Santos-Parker JR, Steward CAC, Bispham NZ, Cuevas LM, Rosenberg HL, Woodward KA, Chonchol M, Gioscia-Ryan RA, Murphy MP, Seals DR. Chronic Supplementation With a Mitochondrial Antioxidant (MitoQ) Improves Vascular Function in Healthy Older Adults. Hypertension. 2018 Jun;71(6):1056-1063. doi: 10.1161/HYPERTENSIONAHA.117.10787. Epub 2018 Apr 16. PMID: 29661838; PMCID: PMC5945293.